If you’re adding or subtracting a spice or using gluten-free flour blends instead of whole wheat flour, you shouldn’t run into problems. Changing main ingredients, however, changes everything so I generally advise against it.
I also advise against trying to de-veganize a recipe since they're created vegan from inception and changing chemistry leads to bad baking. For example I find with whole wheat flours I don't need a binder which is what eggs generally do so something in my recipe, like a banana or applesauce, is not necessary replacing anything and is most likely needed for the goodies to come out right. Why not give healthy vegan food a chance?